ceesdekker.net - An Overview
ceesdekker.net - An Overview
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Nanotechnology provides A variety of options to lead to biology. Below I'll current illustrations wherever nanofabrication – a chance to make confined buildings with dimensions at will – is utilized to examine the biophysics of single molecules and cells. I will present some examples from our lab:
You regularly get involved in conversations about science and religion. You have got also written several publications on the subject. Don’t you are convinced at some time We'll know everything and that God’s role is going to be over?
[Laughs] ‘It absolutely was unquestionably an awesome hazard! At some time, I had been very well knowledgeable that it could go Completely wrong Which I could come to be significantly less prosperous, but I just overlooked that. Curiosity has constantly been my strongest driving power. And luckily it all labored out.’
Given that 2000, Dekker has shifted the leading concentrate of his operate towards biophysics in which he experiments the properties of single biomolecules and cells utilizing the resources of nanotechnology. This modification of industry was driven by his fascination for your impressive performing of Organic molecular structures, along with with the extensive-term perspective that a lot of exciting discoveries is usually expected in this area.[5] Existing lines of analysis in his biophysics group are while in the regions of:[six]
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Our analysis ranges from your biophysics of DNA to synthetic cells and past. Remember to have a look beneath in the spectrum of our present tasks.
Numerous associated developments followed, exactly where our group proven diverse transistor variants for instance one-electron transistors at place temperature and intramolecular nanotube junctions that acted as rectifying diodes, and coupled various transistors into compact evidence-of-basic principle Digital circuits.
Dynamic ParB–DNA interactions initiate and sustain a partition condensate for bacterial chromosome segregation
‘Indeed, I understand persons had been amazed at the time. At the end of the nineties, After i was in my forties, I was Professor of Molecular Electronics and I've to admit that it experienced turn into a bit bored, I didn’t find out Considerably anymore. The field went far more into the applying side, how you might combine nanotubes into electronic circuits.
Presently, we also understood that it ought to be probable to employ only one semiconducting carbon nanotube for making a transistor — and we established out to really make it. We stretched personal semiconducting nanotubes across metallic electrodes and employed the underlying silicon substrate as being a gate electrode, establishing The essential a few-terminal format of a area-result transistor (Fig.
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Cees Dekker is Distinguished University Professor at TU Delft. Experienced for a physicist, he pioneered nanotechnology with lots of discoveries on carbon nanotubes in the 1990s. Because 2000, he moved to single-molecule biophysics and nanobiology. His current study focuses on (i) nanopores for protein sequencing; (ii) chromosome structure, in particular SMC motor protein; and (iii) developing a dwelling artificial cell from lifeless molecules. Dekker is surely an elected member in the KNAW and fellow for the APS as well as the IOP.
As an example, we look at the nucleopore complicated, a gateway in between the mobile nucleus plus the cytoplasm. This is an extremely difficult method and therefore tricky to review in the cell, so we use biomimetics. We reconstruct holes after which you can insert particular person aspects in the nucleopore complicated to check transportation by it at The only-molecule level.’
‘I am pushed by question and queries. On a fabric stage I obtain answers in physics, but I knowledge my deepest joy with God. That faith also drives my science And just how I contend with individuals.